2021



Levy, T.; Marchand, L.; Stroobant, V.; Pilotte, L.; Van den Eynde, B.; Rodriguez, F.; Delfourne, E. IDO1 and TDO Inhibitory Evaluation of Analogues of the Marine Pyrroloiminoquinone Alkaloids: Wakayin and Tsitsikammamines.
Bioorg. Med. Chem. 2021, 40, 127910.
BioorgMedChem2021
BioorgMedChem2021


Farjallah, A.; Chiarelli, L. R.; Forbak, M.; Degiacomi, G.; Danel, M.; Goncalves, F.; Carayon, Seguin, C.; Fumagalli, M.; Zahorszka, M.; Vega, E.; Abid, S.; Grzegorzewicz, A.; Jackson, M.; Peixoto, A.; Kordulakova, J.; Pasca, M. R.; Lherbet, C.; Chassaing, S. A Coumarin-Based Analogue of Thiacetazone as Dual Covalent Inhibitor and Potential Fluorescent Label of HadA in Mycobacterium tuberculosis.
ACS Infect. Dis. 2021, 7, 552-565.
ACSInfectDis2021
ACSInfectDis2021


Carayon, C.; Andre-Barres, C.; Leygue, N.; Saffon-Merceron, N.; Boggio-Pasqua, M.; Fery-Forgues, S. The role of the synthetic chromophore of GFP in generating polymorphism-​dependent on​/off photoluminescence.
Dyes and Pigments, 2021, 187, 109119.
DyePig2021
DyePig2021


Bourgeade-Delmas, S.; André-Barrès, C.; Lucas, J.; Trinel, M.; Castillo Pareja, D.; Jullian, V. Bioactive Isocedrenes from Perezia multiflora.
Planta Medica 2021, 87, 201-208.
PlantaMedica2021
PlantaMedica2021


Fernández de Luco, J.; Recio-Balsells, A. I.; Ghiano, G.; Bortolotti, A.; Belardinelli, J. M.; Liu, N.; Hoffmann, P.; Lherbet, C.; Tonge, P. J.; Tekwani, B.; Morbidoni, H. R.; Labadie, G. R. Exploring the chemical space of 1,2,3-triazolyl triclosan analogs for discovery of new antileishmanial chemotherapeutic agents.
RSC Med Chem, 2021,12, 120-128.
RSCMedChem2021
RSCMedChem2021


2020


Pepe, D. A.; Toumpa, D.; Andre-Barres, C.; Menendez, C.; Mouray, E.; Baltas, M.; Grellier, P.; Papaioannou, D.; Athanassopoulos, C. M. Synthesis of Novel G Factor or Chloroquine-​Artemisinin Hybrids and Conjugates with Potent Antiplasmodial Activity.
ACS Med. Chem. Lett. 2020, 11, 921-927.
ACSMedChem2020
ACSMedChem2020


Gonnet, L.; Andre-Barres, C.; Guidetti, B.; Chamayou, A.; Menendez, C.; Baron, M.; Calvet, R.; Baltas, M. Study of the two steps and one-​pot two-​step mechanochemical synthesis of annulated 1,​2,​4-​triazoles.
ACS Sustainaible Chem. Eng. 2020, 8, 3114-3125.
ACSSustainable2020
ACSSustainable2020


Doğan, S. D.; Gündüz, M. G.; Doğan, H.; Lherbet, C.; Krishna, V. S.; Sriram, D.; Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors.
Eur. J. Med. Chem. 2020, 199, 112402.
EurJMedChem2020(1)
EurJMedChem2020(1)


Doğan, H.; Doğan, S. D.; Gündüz, M. G.; Krishna, V. S.; Lherbet, C.; Sriram, D.; Şahin, O.; Sarıpınar, E. Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors.
Eur. J. Med. Chem. 2020, 188, 112035.
EurJMedChem2020(2)
EurJMedChem2020(2)


Rodriguez, F.; Saffon, N.; Sammartino, J. C.; Degiacomi, G.; Pasca, M. R.; Lherbet, C. First triclosan-based macrocyclic inhibitors of InhA enzyme.
Bioorg. Chem. 2020, 95, 103498.
BioorgChem2020
BioorgChem2020

2019


Saffon-Merceron, N.; Vigroux, A.; Hoffmann, P. Crystal structure of a 2D coordination framework of formula [Zn(NDC)(DEF)].
Acta Cryst. 2019, E75, 1759-1762.
ActaCryst2019
ActaCryst2019


Joshi, S. D.; Kumar, P. S. R.; Patil, S.; Vijayakumar, M.; Kulkarni, V. H. ; Nadagouda, M. N.; Badiger, A. M. ; Lherbet, C.; Aminabhavi, T. M. Chemical synthesis, molecular modeling and pharmacophore mapping of new pyrrole derivatives as inhibitors of InhA enzyme and Mycobacterium tuberculosis growth.
Med. Chem. Res. 2019, 28, 1838-1863.

Shaikh, M. S.; Kanhed, A. M.; Chandrasekaran, B.; Palkar, M. B.; Agrawal, N.; Lherbet, C.; Hampannavar, G. A.; Karpoormath, R. Discovery of novel N-methyl carbazole tethered rhodanine derivatives as direct inhibitors of Mycobacterium tuberculosis InhA. Bioorg.
Med. Chem. Lett. 2019, 29, 2338-2344.

Pinzi, L.; Lherbet, C.; Baltas, M.; Pellati, F.; Rastelli, G. In Silico Repositioning of Cannabigerol as a Novel Inhibitor of the Enoyl Acyl Carrier Protein (ACP) Reductase (InhA).
Molecules 2019, 24, E2567.

André-Barrès, C. ; Lalevée, J. ; Anselmi, E. ; Dagousset, G.; Magnier, E.; Gigmes, D.; Tuccio, B. Méthode du spin trapping : la RPE pour la détection d’intermédiaires réactionnels.
L'Actualité Chimique, 2019, 25-29.

Dehoux, C.; Castellan, T.; Enel, M.; André-Barrès, C.; Mirval, S. ; Becq, F. ; Ballereau, S.; Génisson, Y. Transalpinecine and Analogues: First Total Synthesis, Stereochemical Revision and Biological Evaluation.
Eur. J. Org. Chem., 2019, 19, 1830-1834

2018


Joshi, S. D.; Dixit, S. R.; Basha, J.; Kulkarni, V. H.; Aminabhavi, T. M.; Nadagouda, M. N.; Lherbet, C. Pharmacophore mapping, molecular docking, chemical synthesis of some novel pyrrolyl benzamide derivatives and evaluation of their inhibitory activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
Bioorg Chem. 2018, 81, 440-453.

Chollet, A.; Maveyraud, L.; Lherbet, C.; Bernardes-Genisson, V. An overview on crystal structures of InhA protein: apo-form, in complex with its natural ligands and inhibitors.
Eur. J. Med. Chem. 2018, 146, 318-343 (Review).

Suresh, A.; Agnieszka, N.; Ewa, A.-K.; Alvala, M.; Lherbet, C.; Chandra Sekhar, K. V. G. Design, synthesis of 9H-fluorenone based 1,2,3-triazole analogues as Mycobacterium tuberculosis InhA inhibitors.
Chem. Biol. Drug Des. 2018, 91, 1078-1086.

Moulkrere, B. R.; Orena, B. S.; Mori, G.; Saffon-Merceron, N.; Rodriguez, F.; Lherbet, C.; Nadji, B.; Mohamed, A.; Hoffmann, P.; Fodili, M. Evaluation of heteroatom-rich derivatives as antitubercular agents with InhA inhibition properties.
Med. Chem. Res. 2018, 27, 308-320.

Belkheiri, N.; Belkacem, Z.; Derdour, M.; Mechrouch, F.; Bachar, R. M.; Fodili, M.; Amari, M.; Hoffmann P. Synthesis of benzimidazole-cyclohexanone derivatives.
J. Fundam. Appl. Sci. 2018, 10, 213-22.

Hamza, K.; Touati, A.; Ait-Yahia, A.; Baltas, M.; André-Barrès, C.; Moulay, S. Effect of the nature of surfactant on the reactivity of C-N diphenylnitrone towards acrylonitrile in different microemulsion systems.
Chemistry Journal of Moldova; General, Industrial and Ecological Chemistry 2018, 13, 82-88

2017


Anicat, A.; André-Barrès, C.; Delfourne, E. New reaction of formation of the fused tricyclic bispyrroloquinone ring system.
Tetrahedron Lett. 2017, 58, 342-345.

Joshi, S. D.; More, U. A.; Dixit, S. R.; Balmi, S. M.; Kulkarni, B. G.; Ullagaddi, G.; Lherbet, C.; Aminabhavi, T. M. Chemical synthesis and in silico molecular modeling of novel pyrrolylbenzohydrazide derivatives: their biological evaluation against enoyl ACP reductase (InhA) and Mycobacterium tuberculosis.
Bioorg. Chem. 2017, 75, 181-200.

Oliveira, P. F. M.; Guidetti, B.; Chamayou, A.; André-Barrès, C.; Madacki, J.; Kordulaková, J. Mori, G.; Orena, B. S.; Chiarelli, L. R.; Pasca, M. R.; Lherbet, C.; Carayon, C.; Massou, S.; Baron, M.; Baltas, M. Mechanochemical Synthesis and Biological Evaluation of Novel Isoniazid Derivatives with Potent Antitubercular Activity.
Molecules 2017, 22, 1457-1484.

Faille, A.; Gavalda, S.; Slama, N., Lherbet, C.; Guillet, V.; Laval, F.; Quémard, A.; Mourey, L.; Pedelacq, J.-D. Insights into substrate modification by dehydratases from typeI fatty acid and polyketide synthases.
J. Mol. Biol. 2017, 429, 1554-1569.

Martino, R.; Menendez, C.; Balayssac, S.; Martins, N.; Lherbet, C.; Couderc, F.; Gilard, V.; Malet-Martino, M. A revisited structure for nitrosoprodenafil from NMR, mass spectrometry, X-ray and hydrolysis data.
J. Pharm. Biomed. Anal. 2017, 135, 31-49.

Joshi, S. D.; Dixit, S. R.; Kulkarni, V. H.; Lherbet, C.; Nadagouda, M.; Aminabhavi, T. M. Synthesis, biological evaluation and in silico molecular modeling of pyrrolyl benzohydrazide derivatives as enoyl ACP reductase inhibitors.
Eur. J. Med. Chem. 2017, 126, 286-297.